Resident Evil 4 Remake Regenerators [All You Need To Know]

Resident Evil 4 Remake brings back the infamous Regenerators, and I'll tell you all you need to know about them and how to kill them.

Regeneradors, also known as Regenerators, are far more deadly in the Resident Evil 4 Remake. The Regenerators in the remake have received significant enhancements, and while they were always terrifying due to their otherworldly appearance, their stride, and their capability to withstand countless dismemberments, they are now far more horrifying.

Key Takeaways

  • Regenerators can also crawl on the ground at an amazingly fast pace after having one of their legs blown off.
  • To permanently take them down, players will have to use the Biosensor scope to identify and shoot the parasites residing within their bodies.
  • Their counterparts, the more horrifying Iron Maiden show up in Chapter 14 and even further as a side quest for the Merchant titled “The Wandering Dead“.
Hideous aren’t they? || Images by us: VeryAliGaming

How To Kill Regenerators

Save your ammo when dealing with Regenerators. They regrow limbs, so dismembering is ineffective. To defeat them, target the invisible parasites within their bodies using the Biosensor Scope to conserve ammo.

Images by us: VeryAliGaming
  1. To acquire the Biosensor scope, players need the level 2 keycard from the Incubation Lab, which involves facing Regenerators without the scope, requiring substantial ammo.
  2. Once obtained, attach the scope to an assault rifle.
  3. Use the scope to locate and shoot the parasites within the Regenerators to eliminate them permanently.
  4. The parasites glow orange through the scope, and once all are eliminated, the Regenerators will explode and collapse.

Here are some tips I have gathered that might help you:

  1. Use shotguns and grenades to dismember them and slow them down
  2. Using a knife is one approach to expose a Regenerator’s weak points. If you try to slice this monster from behind, it will produce a reddish glow if you strike an area close to a parasite.
  3. Be careful; shooting their legs might stun them, but they will lunge at you even then.
Shoot the Glowy bits || Images by us: VeryAliGaming

Doing this will be required to obtain the Wrench Tool, which is essential to progress further in the story. Just fire at the pod to shatter the glass, eject the regenerator with the tool inside its body, and get ready to battle.

Again, I advise to stay as far away from these monsters as you can, so don’t shatter more pods than you have to unless you have a death wish. 

Iron Maiden Regenerators – Mutated 2nd Form

Just if things were not already enough, Regenerators transform into the more terrifying Iron Maidens. Initially appearing dead, they resurrect as Iron Maidens, resembling Regenerators but with noticeable sharp spikes.

Unlike before, they can shoot needles and pull in targets. Take cover instead of relying on distance to stay safe.

Those with needle phobias, be careful || Images by us: VeryAliGaming
  1. In Chapter 14, prepare ample rifle ammo to face the Iron Maiden, similar to the standard Regenerator.
  2. Use the biosensor scope to target the parasites in their head if they transform.
  3. Aim for their weak points and stun them by shooting their head.
  4. Alternatively, remove their legs with a shotgun or grenade, then use the scope from a distance to finish them.
  5. Beware of their ability to use spikes even when grounded. When defeated, they explode violently, so take cover behind a corner.

The Wandering Dead Side Quest

You may also come across a blue request mission called “The Wandering Dead” which appears atop a box in the Cargo Depot’s second half, after Ashley smashes the depot wall.

It mentions a strange wandering body needing elimination and directs to deal with a “strong threat” in the Incubation Lab. These threats resemble Regenerators but are more dangerous, inflicting serious damage with their spikes if approached closely.

Images by us: VeryAliGaming
  1. To complete this quest, you’ll need to make your way to the Incubation Lab.
  2. Once there, multiple Regenerators are present, rather than killing them all (you can still do it if you wish), focus on the Spiked one.
  3. To make this fight as easy as possible, you’ll need a good supply of rifle ammunition, a fully tuned Stingray, and the Bio-Sensor Scope you discovered when you were in the surrounding areas earlier. 

My Recommendations And Tricks

Players can choose to attach the Biosensor Scope to either the Stingray, CQBR Assault Rifle, or even the LE-5 submachine gun. Unless you have the exclusive upgrade, the LE 5 lacks the penetrative power of a rifle but makes up for it with an extremely rapid rate of fire and is far more effective in close quarters. 

When you’ve finished the Wandering Dead task, you may want to see Merchant to receive your x8 spinel reward.

Now that you are here, why not read on:

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